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Proteins and Peptides

Human SMN1 Protein, His Tag

Product Sizes
100 ug
£318.00
SM1-H5145-100UG
1 mg
£2108.00
SM1-H5145-1MG
About this Product
SKU:
SM1-H5145
Buffer:
PBS, 0.5 M Arginine, pH7.4
Extra Details:
SMN1 is produced chiefly by the SMN1 gene, located on the telomeric portion of chromosome 5q. SMN1 protein is one of a group of proteins called the SMN complex, which is important for the maintenance of specialized nerve cells called motor neurons. In cells, the SMN complex plays an important role in processing mRNA. The SMN complex helps to assemble the cellular machinery needed to process pre-mRNA. The SMN complex is also important for the development of specialized outgrowths from nerve cells called dendrites and axons. Deletion or mutation of the SMN1 gene results in a reduced level of full-length SMN protein and manifests as a range of neuromuscular phenotypes in humans as the disease spinal muscular atrophy (SMA).
Immunogen:
SMN1
Molecular Weight:
33.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human SMN1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human SMN1, His Tag (Cat. No. SM1-H5145) at 1 ug/mL (100 uL/well) can bind Anti-SMN1 antibody with a linear range of 0.2-8 ng/mL (QC tested).