Human SIGIRR Protein, Fc Tag (MALS verified)
Product Sizes
100 ug
£307.00
SIR-H5255-100UG
1 mg
£2108.00
SIR-H5255-1MG
About this Product
- SKU:
- SIR-H5255
- Additional Names:
- interleukin-1 receptor 8|Single Ig IL-1-related receptor|Single Ig IL-1R-related molecule|Single immunoglobulin domain-containing IL1R-related protein|TIR8|Toll
- Buffer:
- PBS
- Extra Details:
- Single immunoglobulin IL-1-related receptor (SIGIRR), which is also known as Toll/interleukin-1 receptor 8, is a member of the interleukin-1 receptor (IL-1R) family. SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
- Immunogen:
- SIGIRR
- Molecular Weight:
- 39.0 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
