Biotinylated Human Siglec-8 Protein, His,Avitag[TM]
Product Sizes
25 ug
£377.00
SI8-H82E9-25UG
200 ug
£1614.00
SI8-H82E9-200UG
About this Product
- SKU:
- SI8-H82E9
- Additional Names:
- SAF-2|SAF2|Siglec-8|SIGLEC8
- Buffer:
- PBS, 0.5 M Arginine, pH7.4
- Conjugate:
- Biotin
- Extra Details:
- Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8. Siglec-8 was first identified by CD33 homology screening of ESTs from a cDNA library generated from a patient diagnosed with idiopathic hypereosinophilic syndrome and was originally termed SAF-2 (sialoadhesin family 2). At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Two splice variants of Siglec-8 exist. The initially characterized form contains 431 amino acid residues in total, subsequently, a longer form of Siglec-8, initially termed Siglec-8L. Both forms of Siglec-8 are found in eosinophils and contain a V-set domain with lectin activity and two C2-type Ig repeat domains in the extracellular region.
- Immunogen:
- Siglec-8
- Molecular Weight:
- 41.4 kda
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
