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Proteins and Peptides

Human Siglec-10 Protein, Fc (L118A, G120A, E201A) Tag

Product Sizes
100 ug
£413.00
SI0-H5255-100UG
1 mg
£2703.00
SI0-H5255-1MG
About this Product
SKU:
SI0-H5255
Additional Names:
MGC126774|PRO940|SIGLEC10|SLG2
Buffer:
PBS
Extra Details:
The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
Immunogen:
Siglec-10
Molecular Weight:
84.6 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human Siglec-10, Fc (L118A, G120A, E201A) Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.
Immobilized Human Siglec-10, Fc (L118A, G120A, E201A) Tag (Cat. No. SI0-H5255) at 5 ug/mL (100 uL/well) can bind Anti-Siglec-10 Antibody, Human IgG1 with a linear range of 0.2-6 ng/mL (QC tested).