Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout

Mouse Siglec-15 / CD33L3 Protein, His Tag

Product Sizes
100 ug
£377.00
SG5-M52H7-100UG
1 mg
£2703.00
SG5-M52H7-1MG
About this Product
SKU:
SG5-M52H7
Additional Names:
CD33 antigen-like 3|CD33L3|sialic acid-binding Ig-like lectin 15|SIGLEC-15|Siglec15
Buffer:
PBS with Arginine, pH7.4
Extra Details:
Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
Immunogen:
Siglec-15
Molecular Weight:
27.5 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Lectins
Mouse Siglec-15, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Mouse Siglec-15, His Tag (Cat. No. SG5-M52H7) at 5 ug/mL (100 uL/well) can bind Monoclonal Anti-Human Siglec-15 (5G12) Antibody, Human IgG1 with a linear range of 0.3-5 ng/mL (QC tested).
Immobilized Mouse Siglec-15, His Tag (Cat. No. SG5-M52H7) at 10 ug/mL (100 uL/well) can bind Neu5Ac(a2-6)GalNAc-PAA-biotin with a linear range of 0.078-1.25 ug/mL (Routinely tested).