Human P-Selectin / CD62P Protein, Fc Tag
Product Sizes
100 ug
£277.00
SEP-H5255-100UG
1 mg
£1696.00
SEP-H5255-1MG
About this Product
- SKU:
- SEP-H5255
- Additional Names:
- CD62P|GMP-140|P-Selectin|SELP
- Buffer:
- Tris with Glycine, Arginine and NaCl, pH7.5
- Extra Details:
- P-selectin (SELP) is also known as CD62 antigen-like family member P, granule membrane protein 140 (GMP-140), leukocyte-endothelial cell adhesion molecule 3 (LECAM3) and platelet activation dependent granule-external membrane protein (PADGEM). SELP functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets SELP is stored in A Alpha-granules. The primary ligand for SELP is P-selectin glycoprotein ligand-1 (PSGL-1) which is expressed on almost all leukocytes, although P-selectin also binds to heparan sulfate and fucoidan. Furthermore, SELP has a functional role in metastasis of tumor similar to E-selectin, which can help cancer cells invade into bloodstream for metastasis and provided locally with multiple growth factors respectively.
- Immunogen:
- P-Selectin
- Molecular Weight:
- 106.6 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Lectins
