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Proteins and Peptides

Human R-Spondin 1 / RSPO1 (21-146) Protein, His Tag, premium grade

Product Sizes
20 ug
£185.00
RS6-H4220-20UG
50 ug
£218.00
RS6-H4220-50UG
1 mg
£1384.00
RS6-H4220-1MG
About this Product
SKU:
RS6-H4220
Additional Names:
CRISTIN3|FLJ40906|R-spondin-1|RP11-566C13.1|RSPO1
Buffer:
PBS
Extra Details:
R-spondin-1 is also known as Roof plate-specific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), which is a secreted protein which belongs to the R-Spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/B Beta-catenin signaling, but have distinct expression patterns. Like other R-Spondins, R-Spondin-1 contains two adjacent cysteinerich furinlike domains (aa 34-135) with one potential N-glycosylation site, followed by a thrombospondin (TSP1) motif (aa 147-207) and a region rich in basic residues (aa 211-263). Only the furinlike domains are needed for B Beta-catenin stabilization. A putative nuclear localization signal at the C-terminus may allow some expression in the nucleus.
Immunogen:
R-Spondin 1
Molecular Weight:
14.6 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human R-Spondin 1 (21-146), His Tag, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human R-Spondin 1 (21-146), His Tag, premium grade (Cat. No. RS6-H4220) at 5 ug/mL (100 uL/well) can bind Human RNF43, Fc Tag (Cat. No. RN3-H5256) with a linear range of 0.01-0.156 ug/mL (QC tested).
Immobilized Human R-Spondin 1 (21-146), His Tag, premium grade (Cat. No. RS6-H4220) at 5 ug/mL (100 uL/well) can bind Human LRP-6 (20-630), Mouse IgG2a Fc Tag (Cat. No. LR6-H5253) with a linear range of 0.039-2.5 ug/mL (Routinely tested).