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Proteins and Peptides

Human R-Spondin 1 / RSPO1 Protein, His Tag

Product Sizes
50 ug
£377.00
RS1-H4221-50UG
1 mg
£3504.00
RS1-H4221-1MG
About this Product
SKU:
RS1-H4221
Additional Names:
CRISTIN3|FLJ40906|R-spondin-1|RP11-566C13.1|RSPO1
Buffer:
PBS
Extra Details:
R-spondin-1 is also known as Roof plate-specific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), which is a secreted protein which belongs to the R-Spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/B Beta-catenin signaling, but have distinct expression patterns. Like other R-Spondins, R-Spondin-1 contains two adjacent cysteinerich furinlike domains (aa 34-135) with one potential N-glycosylation site, followed by a thrombospondin (TSP1) motif (aa 147-207) and a region rich in basic residues (aa 211-263). Only the furinlike domains are needed for B Beta-catenin stabilization. A putative nuclear localization signal at the C-terminus may allow some expression in the nucleus.
Immunogen:
R-Spondin 1
Molecular Weight:
28.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human R-Spondin 1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human R-Spondin 1, His Tag (Cat. No. RS1-H4221) at 5 ug/mL (100 uL/well) can bind Human SCARB2, Fc Tag (Cat. No. SC2-H5250) with a linear range of 0.02-1.25 ug/mL (QC tested).
Immobilized Human R-Spondin 1, His Tag (Cat. No. RS1-H4221) at 5 ug/mL (100 uL/well) can bind Biotinylated Human CD36, His,Avitag (Cat. No. CD6-H82E9) with a linear range of 0.01-1.25 ug/mL (Routinely tested).