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Biotinylated Human TNFSF11 / RANKL / CD254 Protein, Avitag[TM],Fc Tag

Product Sizes
25 ug
£377.00
RAL-H82F9-25UG
200 ug
£1614.00
RAL-H82F9-200UG
About this Product
SKU:
RAL-H82F9
Additional Names:
CD254|ODF|OPGL|RANKL|TRANCE
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
Receptor activator of nuclear factor kappa-B ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF), is known as a type II membrane protein and is a member of the tumor necrosis factor (TNF) superfamily. RANKL, through its ability to stimulate osteoclast formation and activity, is a critical mediator of bone resorption and overall bone density. Some findings also suggestion some cancer cells, particularly prostate cancer cells, can activate an increase in bone remodeling and ultimately increase overall bone production.[17] This increase in bone remodeling and bone production increases the overall growth of bone metastasizes. The overall control of bone remodeling is regulated by the binding of RANKL with its receptor or its decoy receptor, respectively, RANK and OPG.
Immunogen:
TNFSF11
Molecular Weight:
49.2 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human TNFSF11, Avitag,Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human RANK, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. RAK-H5251) at 0.5 ug/mL (100 uL/well) can bind Biotinylated Human TNFSF11, Avitag,Fc Tag (Cat. No. RAL-H82F9) with a linear range of 0.4-13 ng/mL (QC tested).
Immobilized Human OPG, Fc Tag (Cat. No. TNB-H5259) at 2 ug/mL (100 uL/well) can bind Biotinylated Human TNFSF11, Avitag,Fc Tag (Cat. No. RAL-H82F9) with a linear range of 0.3-10 ng/mL (Routinely tested).