Human RANK / TNFRSF11A Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)
Product Sizes
100 ug
£413.00
RAK-H5251-100UG
1 mg
£2709.00
RAK-H5251-1MG
About this Product
- SKU:
- RAK-H5251
- Additional Names:
- CD265|CD265 antigen|FEO|LOH18CR1|NFKB activator|ODFR|ODFROSTS|OFE|OPTB7|OSTS|PDB2|RANK|RANKLOH18CR1|TNFRSF11A|TRANCER
- Buffer:
- Tris with Glycine, Arginine and NaCl, pH7.5
- Extra Details:
- RANK / TNFRSF11A is a member of the tumor necrosis factor receptor family. RANK / TNFRSF11A shares significant amino acid homology with other members of the TNF R family in its extracellular four cysteine-rich repeats. Functional genomics in mice showed that RANKL (TNFSF11), a member of the TNF ligand superfamily, and RANK (TNFRSF11a), the cognate TNFR family receptor for RANKL, were essential for osteoclastogenesis in vivo. A functional interaction between RANKL, expressed by bone stromal cells of the osteoblast lineage, and RANK, expressed by osteoclast precursors of hematopoietic myeloid lineage, is necessary for osteoclast differentiation, survival, and activation.
- Immunogen:
- RANK
- Molecular Weight:
- 47.2 kda
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
