Human PTP4A3 Protein, His Tag (MALS verified)
Product Sizes
50 ug
£466.00
PT3-H5143-50UG
500 ug
£2685.00
PT3-H5143-500UG
About this Product
- SKU:
- PT3-H5143
- Buffer:
- PBS, 0.2 M Arginine, pH7.4
- Extra Details:
- PTP4A3 (Protein Tyrosine Phosphatase 4A3) is an oncogenic phosphatase that promotes tumor metastasis by enhancing cell migration, invasion, and survival. It is overexpressed in multiple cancers (e.g., breast, ovarian, colorectal) and correlates with poor prognosis. PTP4A3 activates Rho GTPases and downstream pathways (ROCK/LIMK/cofilin) to remodel the actin cytoskeleton, facilitating cancer cell dissemination. Its dual cysteine-based catalytic domain dephosphorylates key signaling proteins, driving aggressive phenotypes. Targeting PTP4A3 offers therapeutic potential for inhibiting metastasis.
- Immunogen:
- PTP4A3
- Molecular Weight:
- 21.1 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
