FITC-Labeled Human PSMA / FOLH1 Protein, His Tag
Product Sizes
25 ug
£342.00
PSA-HF244-25UG
200 ug
£2314.00
PSA-HF244-200UG
About this Product
- SKU:
- PSA-HF244
- Additional Names:
- FGCP|FOLH|FOLH1|GCPII|GIG27|NAALAD1|NAALADase I|PSM|PSMA
- Buffer:
- 25 mM MES, 500 mM NaCl, pH6.5
- Conjugate:
- FITC
- Extra Details:
- Prostate-specific membrane antigen (PSMA) is also known as Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), N-acetylated-alpha-linked acidic dipeptidase I (NAALAD1), which belongs to the peptidase M28 family and M28B subfamily. FOLH1 / PSMA is stable at pH greater than 6.5. FOLH1 / PSMA is a type II transmembrane zinc metallopeptidase that is most highly expressed in the nervous system, prostate, kidney, and small intestine. FOLH1 / GCP-2 is homodimer and binds 2 zinc ions per subunit, and required for NAALADase activity. The catalytic activity of PSMA involved in releasing of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly - gamma - glutamates. FOLH1 / GCP-2 / PSMA has both folate hydrolase and N - acetylated - alpha - linked - acidic dipeptidase (NAALADase) activity and has a preference for tri-alpha-glutamate peptides. GCP-2 / PSMA involved in prostate tumor progression and also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
- Immunogen:
- PSMA
- Molecular Weight:
- 81.4 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
