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Proteins and Peptides

Human PSGL-1 / CD162 Protein, His Tag

Product Sizes
100 ug
£413.00
PS1-H52H9-100UG
1 mg
£2838.00
PS1-H52H9-1MG
About this Product
SKU:
PS1-H52H9
Additional Names:
CD162|PSGL1|Selectin P ligand|SELPLG
Buffer:
PBS
Extra Details:
P-selectin glycoprotein ligand 1 (PSGL-1) is also known as Selectin P ligand (SELPLG), CD antigen CD162. PSGL-1 is disulfide-linked homodimer which is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 / SELPLG interacts with P-, E- and L-selectins, through their lectin/EGF domains, is required for promoting recruitment and rolling of leukocytes. These interactions require sialyl Lewis X glycan modification but there is a differing dependence for tyrosine sulfations. Dimerization appears not to be required for P-selectin/SELP binding. PSGL-1 can interact with SNX20, MSN and SYK. PSGL-1 / SELPLG mediate the activation of SYK by SELPLG.
Immunogen:
PSGL-1
Molecular Weight:
30.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins