Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Cynomolgus Prolactin R Protein, His Tag (MALS verified)

Product Sizes
100 ug
£371.00
PRR-C52H3-100UG
1 mg
£2703.00
PRR-C52H3-1MG
About this Product
SKU:
PRR-C52H3
Buffer:
PBS
Extra Details:
The prolactin receptor (PRLR) is a transmembrane protein belonging to the class I cytokine receptor superfamily, widely expressed in mammary gland, reproductive organs, liver, and brain. Signal activation is initiated when a single prolactin (PRL) molecule binds to this pre-dimerized PRLR, inducing a specific conformational change. This triggers the associated JAK2 kinases to phosphorylate each other and the receptor, ultimately leading to the recruitment and activation of downstream STAT5 transcription factors. This precise mechanism governs essential physiological processes, including lactation, reproduction, metabolism, and immune function, and its dysregulation is implicated in diseases such as certain cancers and endometriosis.
Immunogen:
Prolactin R
Molecular Weight:
26.5 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Cynomolgus Prolactin R Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Biotinylated Human Prolactin, Fc,Avitag (Cat. No. PRN-H82F7) at 1 ug/mL (100 uL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 ug/well) plate can bind Cynomolgus Prolactin R Protein, His Tag (Cat. No. PRR-C52H3) with a linear range of 1-39 ng/mL (QC tested).