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Proteins and Peptides

Human Prolactin R / PRLR Protein, Fc Tag

Product Sizes
100 ug
£377.00
PRP-H5251-100UG
1 mg
£2703.00
PRP-H5251-1MG
About this Product
SKU:
PRP-H5251
Additional Names:
PRL-R|PRLR|Prolactin R
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Extra Details:
As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.
Immunogen:
Prolactin R
Molecular Weight:
51.0 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human Prolactin R, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human Prolactin, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. PRN-H5257) at 1 ug/mL (100 uL/well) can bind Human Prolactin R Protein, Fc Tag (Cat. No. PRP-H5251) with a linear range of 2-78 ng/mL (QC tested).
Immobilized Human GH, Tag Free at 2 ug/mL (100 uL/well) can bind Human Prolactin R, Fc Tag (Cat. No. PRP-H5251) with a linear range of 0.4-6 ng/mL (Routinely tested).