Monoclonal Anti-PNU-159682 Antibody, Rabbit IgG (M1E11)
Product Sizes
100 ug
£324.00
PNU-MY2372-100UG
1 mg
£1955.00
PNU-MY2372-1MG
About this Product
- SKU:
- PNU-MY2372
- Buffer:
- PBS (pH 7.4)
- translate.label.attr.clone:
- M1E11
- Clonality:
- Monoclonal
- Extra Details:
- PNU-159682 is a topoisomerase II inhibitor serving as a payload for antibody-drug conjugates (ADCs). Its mechanism of action involves stabilizing the complex formed by topoisomerase II and DNA, blocking DNA repair and replication processes, and thereby inducing cancer cell apoptosis. Some ADCs containing PNU-159682 have entered the preclinical research stage, showing targeted killing activity in solid tumor models, with particularly significant effects on tumors with high topoisomerase II expression.
- Immunogen:
- PNU-159682
- Physical State:
- Powder
- Reactivities:
- Rabbit
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Antibody: Monoclonal Antibody
