Human Hyaluronidase PH-20 / SPAM1 Protein, His Tag (active enzyme)
Product Sizes
25 ug
£342.00
PH0-H5225-25UG
200 ug
£1337.00
PH0-H5225-200UG
1 mg
£3274.00
PH0-H5225-1MG
About this Product
- SKU:
- PH0-H5225
- Additional Names:
- HYA1|HYAL1|HYAL3|HYAL5|PH-20|SPAG15|SPAM1
- Buffer:
- 50 mM Tris, 100 mM NaCl, pH7.5
- Extra Details:
- Hyaluronidase PH-20 is also known as Sperm adhesion molecule 1 (SPAM1) and Sperm surface protein PH-20, which belongs to the glycosyl hydrolase 56 family, SPAM1 / PH-20 is expressed in testis. SPAM-1 / PH20 random hydrolysis of (1->4)-linkages between N - acetyl - beta - D - glucosamine and D-glucuronate residues in hyaluronate. SPAM-1 / PH20 involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. SPAM1 aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
- Immunogen:
- Hyaluronidase PH-20
- Molecular Weight:
- 53.0 kda
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
