Human Progranulin Protein, His Tag, low endotoxin (MALS & SPR verified)
Product Sizes
100 ug
£377.00
PGN-H52H3-100UG
1 mg
£2461.00
PGN-H52H3-1MG
About this Product
- SKU:
- PGN-H52H3
- Buffer:
- PBS
- Extra Details:
- Progranulin, a secreted glycoprotein, is encoded in humans by the single GRN gene. Progranulin consists of seven and a half, tandemly repeated, non-identical copies of the 12 cysteine granulin motif. Many cellular processes and diseases are associated with this unique pleiotropic factor that include, but are not limited to, embryogenesis, tumorigenesis, inflammation, wound repair, neurodegeneration and lysosome function. Haploinsufficiency caused by autosomal dominant mutations within the GRN gene leads to frontotemporal lobar degeneration, a progressive neuronal atrophy that presents in patients as frontotemporal dementia.
- Immunogen:
- Progranulin
- Molecular Weight:
- 63.7 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
