Human Perlecan Protein, His Tag, low endotoxin
Product Sizes
100 ug
£371.00
PEN-H5245-100UG
1 mg
£2703.00
PEN-H5245-1MG
About this Product
- SKU:
- PEN-H5245
- Buffer:
- PBS
- Extra Details:
- Siglec-15 is a transmembrane glycoprotein belonging to the Siglec family, recognized for its sialic acid-binding properties and role in immune regulation. Structurally, its extracellular domain contains two Ig-like domains, and it functionally associates with the signaling adaptors DAP12 and DAP10. Siglec-15 is expressed on immune cells, including osteoclasts, macrophages, and dendritic cells. It exerts its function by binding to its ligand, the sialyl-Tn antigen. This interaction is critical for inducing TGF-beta production by tumor-associated macrophages and plays an essential role in osteoclast formation and TRANCE/RANK Ligand signaling.
- Immunogen:
- Perlecan
- Molecular Weight:
- 12.2 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
