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Proteins and Peptides

Human PDE4A Protein, His Tag (MALS verified)

Product Sizes
50 ug
£972.00
PDA-H55H3-50UG
500 ug
£3056.00
PDA-H55H3-500UG
About this Product
SKU:
PDA-H55H3
Buffer:
50 mM Tris, 150 mM NaCl, pH7.5
Extra Details:
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (PDE4A) is an enzyme that in humans is encoded by the PDE4A gene. It belongs to the PDE family who hydrolyze 3'-5'-cyclic adenosine monophosphate (cyclic AMP) to 5'-adenosine monophosphate (AMP). PDE enzyme family plays a pivotal role in regulating levels of the second messenger cAMP. Consequently, PDE4 inhibitors have been investigated as a therapeutic strategy to enhance cAMP signaling in a broad range of diseases, including several types of cancers, as well as in various neurologic, dermatological, and inflammatory diseases.
Immunogen:
PDE4A
Molecular Weight:
47.1 kDa
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes