Human PD-L2 / B7-DC Protein, His Tag (SPR verified)
Product Sizes
100 ug
£271.00
PD2-H5220-100UG
1 mg
£1,812.00
PD2-H5220-1MG
About this Product
- SKU:
- PD2-H5220
- Additional Names:
- Butyrophilin B7-DC|CD273|PDCD1 ligand 2|PDCD1L2|PDCD1LG2|PDL2|PD-L2
- Buffer:
- PBS, pH7.4
- Extra Details:
- Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
- Molecular Weight:
- 23.4 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins