Biotinylated Human Osteopontin (OPN) Protein, His,Avitag[TM]
Product Sizes
25 ug
£377.00
OPN-H82E8-25UG
200 ug
£1614.00
OPN-H82E8-200UG
About this Product
- SKU:
- OPN-H82E8
- Additional Names:
- BNSP|BSP-1|BSPI|ETA-1|Nephropontin|OPN|Osteopontin|SPP1|Uropontin
- Buffer:
- PBS
- Conjugate:
- Biotin
- Extra Details:
- Osteopontin (OPN) is also known as Secreted phosphoprotein 1 (SPP1), Bone sialoprotein 1, Nephropontin, Urinary stone protein, Uropontin, BNSP, which belongs to the osteopontin family. OPN / SPP1 is a highly negatively charged, extracellular matrix protein that lacks an extensive secondary structure. Full length OPN (OPN-FL) can be modified by thrombin cleavage, which exposes a cryptic sequence, SVVYGLR on the cleaved form of the protein known as OPN-R. Osteopontin / SPP-1 is biosynthesized by a variety of tissue types. OPN is the ligand for integrin alpha-V/beta-3. OPN / SPP1 binds tightly to hydroxyapatite and appears to form an integral part of the mineralized matrix. OPN / SPP1 probably important to cell-matrix interaction. OPN / SPP1 acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
- Immunogen:
- Osteopontin
- Molecular Weight:
- 35.7 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
