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Proteins and Peptides

Human NRG1 Beta 1 Protein, Fc Tag, premium grade

Product Sizes
100 ug
£207.00
NR1-H5268-100UG
1 mg
£1019.00
NR1-H5268-1MG
About this Product
SKU:
NR1-H5268
Additional Names:
ARIA|GGF|HGL|HRG1 beta 1|HRGA|NDF|Neuregulin-1 beta 1|Neuregulin1 beta 1|NRG1|NRG1 Beta 1|SMDF
Buffer:
PBS
Extra Details:
NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specific and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.
Immunogen:
NRG1 Beta 1
Molecular Weight:
53.2 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human NRG1 Beta 1, Fc Tag, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human ErbB3, His Tag (Cat. No. ER3-H5223) at 2 ug/mL (100 uL/well) can bind Human NRG1 Beta 1, Fc Tag, premium grade (Cat. No. NR1-H5268) with a linear range of 0.5-8 ng/mL (QC tested).
Immobilized Human ErbB4, His Tag (Cat. No. ER4-H5221) at 2 ug/mL (100 uL/well) can bind Human NRG1 Beta 1, Fc Tag, premium grade (Cat. No. NR1-H5268) with a linear range of 0.5-8 ng/mL (Routinely tested).