Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Human Neuropilin-1 / NRP1 / CD304 Protein, Fc Tag

Product Sizes
50 ug
£265.00
NR1-H5252-50UG
1 mg
£2055.00
NR1-H5252-1MG
About this Product
SKU:
NR1-H5252
Additional Names:
CD304|Neuropilin-1|NRP|NRP1|VEGF165R
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Extra Details:
Neuropilin-1 (NRP1) is also known as Vascular endothelial cell growth factor 165 receptor (VEGF165R), CD antigen CD304, which belongs to the neuropilin family. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.
Immunogen:
Neuropilin-1
Molecular Weight:
96.5 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human NRP1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human VEGF165, premium grade (Cat. No. VE5-H4210) at 2 ug/mL (100 uL/well) can bind Human NRP1, Fc Tag (Cat. No. NR1-H5252) with a linear range of 0.2-3 ng/mL (QC tested).
Immobilized Human NRP1, Fc Tag (Cat. No. NR1-H5252) at 2 ug/mL (100 uL/well) can bind Biotinylated Human VEGF165, His,Avitag (Cat. No. VE5-H82Q0) with a linear range of 0.008-0.25 ug/mL (Routinely tested).