Human NPTX2 Protein, His Tag (MALS verified)
Product Sizes
100 ug
£377.00
NP2-H52H6-100UG
1 mg
£2461.00
NP2-H52H6-1MG
About this Product
- SKU:
- NP2-H52H6
- Buffer:
- PBS
- Extra Details:
- Neuronal Pentraxin 2 (NPTX2), also named neuronal activity-regulated pentraxin, is a secreted glycoprotein characterized by a cyclic multimeric structure. In vivo, NTPX2 exerts various neurological effects by combining with the transmembrane protein neuronal pen traxin receptor (NPTXR). NPTX2 was thought to play a vital role in transmitting neurotrans mitters and maintaining synaptic plasticity. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
- Immunogen:
- NPTX2
- Molecular Weight:
- 47.7 kda
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
