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Proteins and Peptides

Human NOTCH3 Protein, Fc Tag

Product Sizes
100 ug
£413.00
NO3-H5255-100UG
1 mg
£2703.00
NO3-H5255-1MG
About this Product
SKU:
NO3-H5255
Additional Names:
Notch-3|NOTCH3
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Extra Details:
Notch3 is one of four mammalian Notch proteins, which act as signalling receptors and involve in developmental patterning, cell fate decisions, regulation of cell survival and proliferation. Notch3 could interact with membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Via ligand activation, notch intracellular domain (NICD) is released and forms a transcriptional activator RBPJ/RBPSUH complex, which activates genes of the enhancer of split locus. Consequently, the activation of Notch3 can lead to the implementation of differentiation, proliferation and apoptotic programs
Immunogen:
NOTCH3
Molecular Weight:
71.4 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human NOTCH3, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human NOTCH3, Fc Tag (Cat. No. NO3-H5255) at 1 ug/mL (100 uL/well) can bind Bispecific Antibody (NOTCH2 x NOTCH3) with a linear range of 2-20 ng/mL (QC tested).