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Proteins and Peptides

Human Nectin-4 Protein, Fc Tag (MALS verified)

Product Sizes
100 ug
£377.00
NE4-H5255-100UG
1 mg
£2703.00
NE4-H5255-1MG
About this Product
SKU:
NE4-H5255
Additional Names:
LNIR|NECTIN4|PRR4|PVRL4
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Extra Details:
Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.
Immunogen:
Nectin-4
Molecular Weight:
60.5 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human Nectin-4, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human Nectin-4, Fc Tag (Cat. No. NE4-H5255) at 1 ug/mL (100 uL/well) can bind Enfortumab with a linear range of 0.1-2 ng/mL (QC tested).
Immobilized Human Nectin-4, Fc Tag (Cat. No. NE4-H5255) at 5 ug/mL (100 uL/well) can bind Human Nectin-1, His Tag (Cat. No. PV1-H5223) with a linear range of 0.2-3 ug/mL (QC tested).