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Proteins and Peptides

Human Netrin-1 Protein, His Tag

Product Sizes
100 ug
£377.00
NE1-H52H3-100UG
1 mg
£2703.00
NE1-H52H3-1MG
About this Product
SKU:
NE1-H52H3
Additional Names:
netrin 1|Netrin-1|Netrin1|NTN1|NTN1L
Buffer:
PBS, pH7.4 with NaCl
Extra Details:
Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. Involved in dorsal root ganglion axon projection towards the spinal cord. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
Immunogen:
Netrin-1
Molecular Weight:
67.5 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human Netrin-1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human Netrin-1, His Tag (Cat. No. NE1-H52H3) at 5 ug/mL (100 uL/well) can bind Human Netrin receptor DCC, Fc Tag (Cat. No. NEC-H5254) with a linear range of 1-10 ng/mL (QC tested).