Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Human NKp30 / NCR3 / CD337 Protein, Llama IgG2b Fc Tag, low endotoxin

Product Sizes
100 ug
£401.00
NC3-H5256-100UG
1 mg
£2656.00
NC3-H5256-1MG
About this Product
SKU:
NC3-H5256
Additional Names:
1C7|CD337|LY117|MALS|NCR3|NKp30
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Extra Details:
Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
Immunogen:
NKp30
Molecular Weight:
40.7 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human NKp30, Llama IgG2b Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human NKp30, Llama IgG2b Fc Tag (Cat. No. NC3-H5256) at 5 ug/mL (100 uL/well) can bind Biotinylated Human B7-H6, Fc,Avitag (Cat. No. B76-H82Wb) with a linear range of 0.6-20 ng/mL (QC tested).
Immobilized Human B7-H6, His Tag (Cat. No. B76-H52H8) at 5 ug/mL (100 uL/well) can bind Human NKp30, Llama IgG2b Fc Tag (Cat. No. NC3-H5256) with a linear range of 0.6-78 ng/mL (Routinely tested).