Human Neprilysin / MME / CD10 Protein, Tag Free (active enzyme)
Product Sizes
50 ug
£424.00
MME-H521B-50UG
1 mg
£2573.00
MME-H521B-1MG
About this Product
- SKU:
- MME-H521B
- Additional Names:
- CALLA|CD10|DKFZp686O16152|MGC126681|MGC126707|MME|NEP|Neprilysin|SFE
- Buffer:
- 20 mM Tris, 100 mM NaCl, pH8.0
- Extra Details:
- Cluster of differentiation 10 (CD10) is also known as membrane metallo-endopeptidase, neutral endopeptidase (NEP), Neprilysin, and common acute lymphoblastic leukemia antigen (CALLA), is a 90-110-kDa type II transmembrane glycoprotein normally expressed by a variety of tissues, including epithelial cells of the prostate, kidney, intestine, endometrium, adrenal glands, and lung. This zinc-dependent metalloprotease enzyme cleaves peptide bonds on the amino side of hydrophobic residues and inactivates a variety of physiologically active secreted peptides. CD20 is thought to be the rate-limiting degrading enzyme of amyloid B Beta peptide (AB Beta) whose abnormal misfolding and aggregation in neural tissue has been implicated in the development of Alzheimer's disease (AD). CD10 is also identified as the common acute lymphoblastic leukemia antigen (CALLA) present on leukemic cells of pre-B phenotype, and thus serves as the most important biomarker in the diagnosis of human acute lymphocytic leukemia (ALL).
- Immunogen:
- Neprilysin
- Molecular Weight:
- 80.0 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
