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Proteins and Peptides

Cynomolgus Melanotransferrin / CD228 Protein, His Tag, low Endotoxin (MALS verified)

Product Sizes
100 ug
£419.00
MEN-C52H3-100UG
1 mg
£2985.00
MEN-C52H3-1MG
About this Product
SKU:
MEN-C52H3
Buffer:
PBS
Extra Details:
Melanotransferrin (MTF), also known as CD228, P97, MELTF and MFI2, is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. MTF expression is low in normal tissues but high in tumor and embryonic tissues. In melanoma MTF is associated with tumor metastasis and angiogenesis and upregulated in lung cancer tissue and cell lines. In the brain MTF is expressed in capillary endothelium but also in the reactive microglia associated with senile plaques in Alzheimer's disease (AD).
Immunogen:
Melanotransferrin
Molecular Weight:
77.1 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Cynomolgus Melanotransferrin Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized anti-human Melanotransferrin monoclonal antibody at 1 ug/mL (100 uL/well) can bind Cynomolgus Melanotransferrin Protein, His Tag (Cat. No. MEN-C52H3) with a linear range of 0.2-32 ng/mL (Routinely tested).