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Biotinylated Human MAdCAM-1 Protein, Fc,Avitag[TM] (MALS verified)

Product Sizes
25 ug
£377.00
MAM-H8251-25UG
200 ug
£1466.00
MAM-H8251-200UG
About this Product
SKU:
MAM-H8251
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
The mucosal addressin cell adhesion molecule-1 (MAdCAM-1) takes a key role in the endothelial adhesion and migration of lymphocytes to sites of inflammation in inflammatory disease. In vitro and in vivo data indicate that blockade of the adhesion molecule mucosal address in cell adhesion molecule (MAdCAM) pathway decreases leukocyte homing to the gut by inhibiting the interaction between MAdCAM and its ligand the A Alpha4B Beta7 integrin expressed on lymphocytes.
Immunogen:
MAdCAM-1
Molecular Weight:
61.3 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human MAdCAM-1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human ITGA4&ITGB7 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT7-H52W4) at 5 ug/mL (100 uL/well) can bind Biotinylated Human MAdCAM-1, Fc Tag (Cat. No. MAM-H8251) with a linear range of 0.4-6 ng/mL (QC tested).