Human MANF Protein, His Tag, low endotoxin (MALS verified)
Product Sizes
20 ug
£159.00
MAF-H52H3-20UG
50 ug
£230.00
MAF-H52H3-50UG
500 ug
£1154.00
MAF-H52H3-500UG
About this Product
- SKU:
- MAF-H52H3
- Buffer:
- PBS
- Extra Details:
- MANF is a secreted neurotrophic factor that is expressed in brain, neuronal and certain non-neuronal tissues. It has been shown to promote the survival, growth and function of dopamine-specific neurons. MANF and its structural homolog CDNF each contain a N-terminal, saposin-like, lipid-binding domain, and a carboxyl-terminal domain that is not homologous to previously characterized protein structures. MANF and CDNF can prevent 6-OHDA-induced degeneration of dopaminergic neurons by triggering survival pathways in a rat experimental model of Parkinson's disease. Recombinant Human MANF is an 18.1 kDa protein consisting of 158 amino acids, including 8 cysteine residues.
- Immunogen:
- MANF
- Molecular Weight:
- 20.0 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
