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Proteins and Peptides

Mouse MASP2 (287-685) Protein, His Tag

Product Sizes
100 ug
£954.00
MA2-M51H3-100UG
1 mg
£2826.00
MA2-M51H3-1MG
About this Product
SKU:
MA2-M51H3
Buffer:
50 mM Tris, 0.3 M Arginine, 0.5 M NaCl, pH8.0
Extra Details:
Mannan-binding lectin-associated serine protease 2 (MASP-2) is a member of the lectin pathway of complement and is one of two splice products from the MASP2 gene. The protein is secreted from the liver as a zymogenic protein consisting of 671 residues and circulates at a concentration of approximately 0.41 ug/mL in the serum. MASP-2 is associated with pattern-recognition molecules as a homodimer that is activated by MASP-1 when bound to an activating surface resulting in an A-chain and a B-chain linked by a disulphide bond. MASP-2 is also capable of autoactivating. Activated MASP-2 cleaves C2 and C4, which leads to formation of the C3 convertase, C4b2a, and activation of complement.
Immunogen:
MASP2
Molecular Weight:
45.4 kDa
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Mouse MASP2 (287-685) Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Mouse MASP2 (287-685) Protein, His Tag (Cat. No. MA2-M51H3) at 1 ug/mL (100 uL/well) can bind Anti-MASP2 Reference Antibody, Human IgG4 lambda with a linear range of 0.1-6 ng/mL (QC tested).