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Biotinylated Human LRP-6 (20-630) Protein, His,Avitag[TM]

Product Sizes
25 ug
£377.00
LR6-H82E7-25UG
200 ug
£1614.00
LR6-H82E7-200UG
About this Product
SKU:
LR6-H82E7
Additional Names:
LRP-6|LRP6
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
LRP6 is a transmembrane low-density lipoprotein receptor that shares a similar structure with LRP5. Low-density lipoprotein receptor-related protein 6 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin.
Immunogen:
LRP-6
Molecular Weight:
72.5 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human LRP-6, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human R-Spondin 1, His Tag (Cat. No. RS1-H4221) at 5 ug/mL (100 uL/well) can bind Biotinylated Human LRP-6, His,Avitag (Cat. No. LR6-H82E7) with a linear range of 0.02-0.625 ug/mL (QC tested).
Immobilized Cynomolgus SOST, His Tag at 5 ug/mL (100 uL/well) can bind Biotinylated Human LRP-6, His,Avitag (Cat. No. LR6-H82E7) with a linear range of 1-39 ng/mL (Routinely tested).