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Proteins and Peptides

Human LRRC32 / GARP / Garpin Protein, Fc Tag

Product Sizes
100 ug
£436.00
LR2-H5256-100UG
1 mg
£2921.00
LR2-H5256-1MG
About this Product
SKU:
LR2-H5256
Additional Names:
D11S833E|GARP|Garpin
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Extra Details:
Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naive T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naive T cell proliferation.
Immunogen:
LRRC32
Molecular Weight:
92.4 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human LRRC32, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human LRRC32, Fc Tag (Cat. No. LR2-H5256) at 2 ug/mL (100 uL/well) can bind Cynomolgus Latent TGF-Beta 1 (C33S), His Tag (Cat. No. TG1-C5243) with a linear range of 0.039-1.25 ug/mL (Routinely tested).