Human LIF R / CD118 Protein, Fc Tag
Product Sizes
50 ug
£197.00
LIR-H4252-50UG
200 ug
£366.00
LIR-H4252-200UG
1 mg
£1531.00
LIR-H4252-1MG
About this Product
- SKU:
- LIR-H4252
- Additional Names:
- CD118|FLJ98106|FLJ99923|LIFR|SJS2|STWS|SWS
- Buffer:
- Tris with Glycine, Arginine and NaCl, pH7.5
- Extra Details:
- Leukemia inhibitory factor receptor is also known as LIFR; CD118; FLJ98106; FLJ99923; LIF-R; SJS2; STWS; SWS, is the receptor for leukemia inhibitory factor (LIF). The leukemia inhibitory factor is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIF action appears to be mediated through a high-affinity receptor complex composed of a low-affinity LIF binding chain (LIF receptor) and a high-affinity converter subunit, gp130. Both LIFR and gp130 are members of a family of cytokine receptors that includes components of the receptors for the majority of hematopoietic cytokines and for cytokines that affect other systems, including the ciliary neurotrophic factor, growth hormone and prolactin Defects in LIFR are the cause of Stueve-Wiedemann syndrome (SWS), a severe autosomal recessive condition and belongs to the group of the bent-bone dysplasias.
- Immunogen:
- LIF R
- Molecular Weight:
- 115.5 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
