Human LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag (MALS verified)
Product Sizes
100 ug
£365.00
LI4-H5257-100UG
1 mg
£2,624.00
LI4-H5257-1MG
About this Product
- SKU:
- LI4-H5257
- Additional Names:
- CD85K|HM18|ILT3|LILRB4|LIR5
- Buffer:
- 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
- Extra Details:
- Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
- Molecular Weight:
- 53.3 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins