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Biotinylated Human LGR5 / GPR49 (22-561) Protein, His,Avitag[TM]

Product Sizes
25 ug
£371.00
LG5-H82E4-25UG
200 ug
£1619.00
LG5-H82E4-200UG
About this Product
SKU:
LG5-H82E4
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/B Beta-catenin signaling by enhancing Wnt-induced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3.
Immunogen:
LGR5
Molecular Weight:
64.1 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human LGR5 (22-561) Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human R-Spondin 3 (22-146), His Tag (Cat. No. RS6-H5222) at 5 ug/mL (100 uL/well) can bind Biotinylated Human LGR5 (22-561) Protein, His,Avitag (Cat. No. LG5-H82E4) with a linear range of 2-78 ng/mL (QC tested).
Immobilized Human R-Spondin 3 Protein, Fc Tag (Cat. No. RS3-H5253) at 5 ug/mL (100 uL/well) can bind Biotinylated Human LGR5 (22-561) Protein, His,Avitag (Cat. No. LG5-H82E4) with a linear range of 0.2-5 ng/mL (Routinely tested).