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Proteins and Peptides

Human CD4 / LEU3 Protein, His Tag (MALS verified)

Product Sizes
200 ug
£377.00
LE3-H5228-200UG
1 mg
£1602.00
LE3-H5228-1MG
About this Product
SKU:
LE3-H5228
Additional Names:
CD4|CD4mut|LEU3
Buffer:
PBS
Extra Details:
T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
Immunogen:
CD4
Molecular Weight:
41.51 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human CD4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Ibalizumab at 1 ug/mL (100 uL/well) can bind Human CD4, His Tag (Cat. No. LE3-H5228) with a linear range of 0.8-6 ng/mL (QC tested).
Immobilized Human CD4, His Tag (Cat. No. LE3-H5228) at 1 ug/mL (100 uL/well) can bind Ibalizumab with a linear range of 0.2-13 ng/mL (Routinely tested).