Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Human Kremen-2 protein, His Tag

Product Sizes
100 ug
£442.00
KR2-H52H3-100UG
1 mg
£3044.00
KR2-H52H3-1MG
About this Product
SKU:
KR2-H52H3
Additional Names:
Dickkopf receptor 2|Kremen-2|KREMEN2|Kringle domain-containing transmembrane protein 2|KRM2
Buffer:
PBS, 0.2 M Arginine, pH7.4
Extra Details:
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/B Beta-catenin signaling pathway. Krm1 and its paralog Krm2 share the ability to bind Dkk1 and inhibit Wnt signaling, both processes previously shown to rely on the extracellular domain. Previous studies have shown that Krm2 may be involved in embryonic development, bone formation, neural ridge formation and tumorigenesis and could be a biomarker of grading and a potential therapeutic target in gastric cancer.
Immunogen:
KREMEN2
Molecular Weight:
38.0 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human Kremen-2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human Dkk-1, Fc Tag (Cat. No. DK1-H5258) at 2 ug/mL (100 uL/well) can bind Human Kremen-2, His Tag (Cat. No. KR2-H52H3) with a linear range of 5-78 ng/mL (QC tested).