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Proteins and Peptides

Human Kremen-1 protein, Fc Tag

Product Sizes
100 ug
£466.00
KR1-H5253-100UG
1 mg
£3274.00
KR1-H5253-1MG
About this Product
SKU:
KR1-H5253
Additional Names:
KREMEN|Kringle domain-containing transmembrane protein 1|Kringle-containing protein marking the eye and the nose|KRM1, Dickkopf receptor
Buffer:
PBS
Extra Details:
Kremens are high-affinity receptors for Dickkopf 1 (Dkk1) and regulate the Wnt/B Beta-catenin signaling pathway by down-regulating the low-density lipoprotein receptor-related protein 6 (LRP6). Kremen1 is considered as one component of a membrane complex modulating canonical Wnt signalling through LRP6 in vertebrates. Additionally, KREMEN1 (KRM1) has also been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD).
Immunogen:
KREMEN1
Molecular Weight:
67.4 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human Kremen-1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human Dkk-1, His Tag (Cat. No. DK1-H5221) at 2 ug/mL (100 uL/well) can bind Human Kremen-1, Fc Tag (Cat. No. KR1-H5253) with a linear range of 0.02-0.313 ug/mL (QC tested).