Cynomolgus KLRG1 Protein, His Tag (SPR verified)
Product Sizes
100 ug
£377.00
KL1-C5243-100UG
1 mg
£2461.00
KL1-C5243-1MG
About this Product
- SKU:
- KL1-C5243
- Buffer:
- PBS
- Extra Details:
- The co-inhibitory receptor killer-cell lectin like receptor G1 (KLRG1) is specifically expressed on NK cells and activated CD8+ T-cells and has been postulated to be a marker of senescence. KLRG1+ T cells are a major reason of chronic tissue damage in some autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. In tumors, tumor cells which express E-cadherin or N-cadherin bind to KLRG1 and inhibit the antitumor activity of T and NK cells. Thus, KLRG1 acts as an immunocheckpoint inhibitory receptor.
- Immunogen:
- KLRG1
- Molecular Weight:
- 16.8 kda
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
