Biotinylated Cynomolgus Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein, His,Avitag[TM]&Tag Free (MALS verified)
Product Sizes
25 ug
£165.00
IT7-C82W3-25UG
200 ug
£1060.00
IT7-C82W3-200UG
About this Product
- SKU:
- IT7-C82W3
- Buffer:
- PBS
- Conjugate:
- Biotin
- Extra Details:
- Integrin alpha 4 beta 7 is an integrin family adhesion receptor that shares subunits with alpha 4 beta 1 (VLA4) and the E-Cadherin receptor, alpha E beta 7 . Integrin alpha 4 beta 7, which is critical for homing to intestinal mucosa, is induced during T cell activation in Peyer's patches or mesenteric lymph nodes.Its expression requires signals from local dendritic and stromal cells, including secreted retinoic acid. The HIV-1 envelope protein gp120 binds to the active form of Integrin alpha 4 beta 7, and this may or may not account for the concentration of HIV-1 virus in the gut-associated lymphoid tissue (GALT). Integrin alpha 4 beta 7 may also be involved in lymphocyte trafficking in acute intestinal graft vs. host disease (GVHD).
- Immunogen:
- Integrin alpha 4 beta 7
- Molecular Weight:
- 112.9 kDa (ITGA4) & 81.6 kDa (ITGB7)
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
