Mouse Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein, His Tag&Tag Free
Product Sizes
100 ug
£424.00
IT1-M52W4-100UG
1 mg
£3,271.00
IT1-M52W4-1MG
About this Product
- SKU:
- IT1-M52W4
- Additional Names:
- Integrin alpha 10 beta 1|ITGA10&ITGB1
- Buffer:
- 50 mM Tris, 150 mM NaCl, pH7.5
- Extra Details:
- Human integrin alpha(10)I domain as a recombinant protein to reveal its ligand binding specificity. In general, alpha(10)I did recognize collagen types I-VI and laminin-1 in a Mg(2+)-dependent manner, whereas its binding to tenascin was only slightly better than to albumin. Alpha 10 beta 1 is a known collagen-binding I domain integrin, in addition to A Alpha1B Beta1, A Alpha2B Beta1 and A Alpha11B Beta1. GROGER found in the N-terminal domain of collagens I and III, is only weakly recognised by A Alpha10B Beta1, an important collagen receptor on chondrocytes, contrasting with the other collagen-binding integrins.
- Molecular Weight:
- 126.6 kDa (ITGA10) & 83.5 kDa (ITGB1)
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins