Biotinylated Human Insulin R / CD220 (28-944) Protein, His,Avitag[TM] (MALS & SPR verified)
Product Sizes
25 ug
£377.00
INR-H82E6-25UG
200 ug
£1614.00
INR-H82E6-200UG
About this Product
- SKU:
- INR-H82E6
- Buffer:
- PBS
- Conjugate:
- Biotin
- Extra Details:
- Insulin receptor (INSR) is also known as CD antigen CD220, which can be cleaved into the following 2 chains: Insulin receptor subunit alpha and Insulin receptor subunit beta. INSR is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains carry the insulin-binding regions, while the beta chains carry the kinase domain. Forms a hybrid receptor with IGF1R, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. In addition to binding insulin, the insulin receptor can bind insulin-like growth factors (IGFI and IGFII). Isoform Short of INSR has a higher affinity for IGFII binding. When present in a hybrid receptor with IGF1R, INSR binds IGF1.
- Immunogen:
- Insulin R
- Molecular Weight:
- 108.2 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
