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Proteins and Peptides

Human Integrin alpha 6 beta 4 (ITGA6&ITGB4) Heterodimer Protein, His Tag&Tag Free, low endotoxin (MALS verified)

Product Sizes
100 ug
£436.00
IN4-H52W3-100UG
1 mg
£3068.00
IN4-H52W3-1MG
About this Product
SKU:
IN4-H52W3
Buffer:
50 mM Tris, 150 mM NaCl, 0.2 M Arginine, pH7.5
Extra Details:
Human integrin alpha(10)I domain as a recombinant protein to reveal its ligand binding specificity. In general, alpha(10)I did recognize collagen types I-VI and laminin-1 in a Mg(2+)-dependent manner, whereas its binding to tenascin was only slightly better than to albumin. Alpha 10 beta 1 is a known collagen-binding I domain integrin, in addition to A Alpha1B Beta1, A Alpha2B Beta1 and A Alpha11B Beta1. GROGER found in the N-terminal domain of collagens I and III, is only weakly recognised by A Alpha10B Beta1, an important collagen receptor on chondrocytes, contrasting with the other collagen-binding integrins.
Immunogen:
Integrin alpha 6 beta 4
Molecular Weight:
116.8 kDa | 81.8 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human ITGA6&ITGB4 Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human ITGA6&ITGB4 Heterodimer Protein, His Tag&Tag Free (Cat. No. IN4-H52W3) at 5 ug/mL (100 uL/well) can bind Human Laminin 511 Protein, premium grade (Cat. No. LA8-H5283) with a linear range of 0.8-13 ng/mL (QC tested).
Immobilized Human Laminin 511 Protein, premium grade (Cat. No. LA8-H5283) at 5 ug/mL (100 uL/well) can bind Human ITGA6&ITGB4 Heterodimer Protein, His Tag&Tag Free (Cat. No. IN4-H52W3) with a linear range of 0.01-0.156 ug/mL (Routinely tested).