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Proteins and Peptides

Human IL-11 R alpha Protein, His Tag, low endotoxin (MALS verified)

Product Sizes
100 ug
£377.00
ILR-H52H5-100UG
1 mg
£2703.00
ILR-H52H5-1MG
About this Product
SKU:
ILR-H52H5
Additional Names:
IL-11 R alpha|IL-11 RA|IL-11 receptor subunit alpha|IL-11R subunit alpha|IL-11R-alpha|IL11RA|Interleukin-11 receptor subunit alpha
Buffer:
PBS
Extra Details:
Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
Immunogen:
IL-11 R alpha
Molecular Weight:
39.6 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-11 R alpha, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-11, Fc Tag (Cat. No. IL1-H5269) at 5 ug/mL (100 uL/well) can bind Human IL-11 R alpha, His Tag (Cat. No. ILR-H52H5) with a linear range of 0.008-0.5 ug/mL (Routinely tested).