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Proteins and Peptides

Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag

Product Sizes
100 ug
£448.00
ILR-H525X-100UG
1 mg
£2768.00
ILR-H525X-1MG
About this Product
SKU:
ILR-H525X
Additional Names:
CD127|CRL2|CRLF2|CRLF2 fusion|CRLF2Y|Cytokine receptor-like 2|IL-XR|IL7Ra|ILXR|p2RY8|TSLP R|TSLP receptor|TSLPR
Buffer:
PBS
Extra Details:
TSLP is a pleiotropic cytokine originally characterized as a lymphocyte growth factor. Thymic stromal lymphopoietin (TSLP) is overexpressed in the airways of severe asthmatics and is an upstream cytokine that orchestrates inflammatory responses in asthma. Human TSLP exerts its biological activities by binding to a high-affinity heteromeric receptor complex composed of TSLPR and IL- 7 receptor and initiates signaling in cells co-expressing TSLPR and IL-7R.
Immunogen:
IL-7 R alpha & TSLP R
Molecular Weight:
51.7 kDa (IL-7 RA) & 50.3 kDa (TSLP R)
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. ILR-H525x) at 5 ug/mL (100 uL/well) can bind Biotinylated Human TSLP, His,Avitag (Cat. No. TSP-H82Eb) with a linear range of 0.1-2 ng/mL (QC tested).
Serial dilutions of Monoclonal Anti-Human TSLP Antibody, Human IgG2 were added into Human IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. ILR-H525x) : Biotinylated Human TSLP, His,Avitag (Cat. No. TSP-H82Eb) binding reactions. The half maximal inhibitory concentration (IC50) is 0.21312 ug/mL (Routinely tested).