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Proteins and Peptides

Cynomolgus IL-4 R alpha & IL-13 R alpha 1 Protein, His Tag&His Tag (MALS verified)

Product Sizes
100 ug
£448.00
ILR-C52H9-100UG
1 mg
£3403.00
ILR-C52H9-1MG
About this Product
SKU:
ILR-C52H9
Buffer:
PBS
Extra Details:
Interleukin 4 Receptor (IL4R) also known as CD124, IL4RA Alpha and BSF receptor, is a type I cytokine receptor produced by activated Th2 cells and mast cells, and plays an important role in Th2--biased immune responses, alternative macrophage activation, mucosal immunity, allergic inflammation, tumor progression, and atherogenesis. A soluble form of the encoded IL4R protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. IL4R can alternatively associate with IL-13Ra1 to form the type II receptor which is responsive to both IL-4 and IL-13. Interleukin-4 receptor has been shown to interact with SHC1.
Immunogen:
IL-4 R alpha & IL-13 R alpha 1
Molecular Weight:
29.0 kDa & 41.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Cynomolgus IL-4 R alpha & IL-13 R alpha 1 Protein, His Tag&His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Cynomolgus IL-4, Fc Tag (Cat. No. IL4-C5259) at 5 ug/mL (100 uL/well) can bind Cynomolgus IL-4 R alpha & IL-13 R alpha 1 Protein, His Tag&His Tag (Cat. No. ILR-C52H9) with a linear range of 1-39 ng/mL (QC tested).